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A high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation

Relaxases act as DNA selection sieves in conjugative plasmid transfer. Most plasmid relaxases belong to the HUH endonuclease family. TrwC, the relaxase of plasmid R388, is the prototype of the HUH relaxase family, which also includes TraI of plasmid F. In this article we demonstrate that TrwC proces...

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Detalhes bibliográficos
Main Authors: Carballeira, José Daniel, González-Pérez, Blanca, Moncalián, Gabriel, de la Cruz, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176350/
https://ncbi.nlm.nih.gov/pubmed/25123661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku741
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