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Multivariate inference of pathway activity in host immunity and response to therapeutics

Developing a quantitative view of how biological pathways are regulated in response to environmental factors is central for understanding of disease phenotypes. We present a computational framework, named Multivariate Inference of Pathway Activity (MIPA), which quantifies degree of activity induced...

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Bibliografiske detaljer
Main Authors: Goel, Gautam, Conway, Kara L., Jaeger, Martin, Netea, Mihai G., Xavier, Ramnik J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176341/
https://ncbi.nlm.nih.gov/pubmed/25147207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku722
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