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Rho GTPases RhoA and Rac1 Mediate Effects of Dietary Folate on Metastatic Potential of A549 Cancer Cells through the Control of Cofilin Phosphorylation

Folate, an important nutrient in the human diet, has been implicated in cancer, but its role in metastasis is not established. We have shown previously that the withdrawal of medium folate leads to the inhibition of migration and invasion of A549 lung carcinoma cells. Here we have demonstrated that...

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Detalhes bibliográficos
Main Authors: Oleinik, Natalia V., Helke, Kristi L., Kistner-Griffin, Emily, Krupenko, Natalia I., Krupenko, Sergey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176232/
https://ncbi.nlm.nih.gov/pubmed/25086046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.569657
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