miR-15b/16-2 Regulates Factors That Promote p53 Phosphorylation and Augments the DNA Damage Response following Radiation in the Lung

MicroRNAs (miRNAs) are regulatory RNAs frequently dysregulated in disease and following cellular stress. Investigators have described changes in miR-15b expression following exposure to several stress-inducing anticancer agents, including ionizing radiation (IR), etoposide, and hydrogen peroxide. Ho...

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Autores principales: Rahman, Mohammad, Lovat, Francesca, Romano, Giulia, Calore, Federica, Acunzo, Mario, Bell, Erica Hlavin, Nana-Sinkam, Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176210/
https://ncbi.nlm.nih.gov/pubmed/25092292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573592
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