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Computational identification of RNA functional determinants by three-dimensional quantitative structure–activity relationships
Anti-infection drugs target vital functions of infectious agents, including their ribosome and other essential non-coding RNAs. One of the reasons infectious agents become resistant to drugs is due to mutations that eliminate drug-binding affinity while maintaining vital elements. Identifying these...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176186/ https://ncbi.nlm.nih.gov/pubmed/25200082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku816 |
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