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Distinct tmRNA sequence elements facilitate RNase R engagement on rescued ribosomes for selective nonstop mRNA decay

trans-Translation, orchestrated by SmpB and tmRNA, is the principal eubacterial pathway for resolving stalled translation complexes. RNase R, the leading nonstop mRNA surveillance factor, is recruited to stalled ribosomes in a trans-translation dependent process. To elucidate the contributions of Sm...

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Detalhes bibliográficos
Main Authors: Venkataraman, Krithika, Zafar, Hina, Karzai, A. Wali
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176180/
https://ncbi.nlm.nih.gov/pubmed/25200086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku802
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