Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis

BACKGROUND: Basal-like breast cancer is a heterogeneous disease characterized by the expression of basal cell markers, no estrogen or progesterone receptor expression and a lack of HER2 ov erexpression. Recent studies have linked activation of the Wnt/β-catenin pathway, and its downstream target, My...

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Autores principales: Moumen, Mejdi, Chiche, Aurélie, Decraene, Charles, Petit, Valérie, Gandarillas, Alberto, Deugnier, Marie-Ange, Glukhova, Marina A, Faraldo, Marisa M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176121/
https://ncbi.nlm.nih.gov/pubmed/24171719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-132
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