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Forecasting Cell Death Dose-Response from Early Signal Transduction Responses In Vitro
The rapid pharmacodynamic response of cells to toxic xenobiotics is primarily coordinated by signal transduction networks, which follow a simple framework: the phosphorylation/dephosphorylation cycle mediated by kinases and phosphatases. However, the time course from initial pharmacodynamic response...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176052/ https://ncbi.nlm.nih.gov/pubmed/24824809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu089 |
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