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Talpid3-Binding Centrosomal Protein Cep120 Is Required for Centriole Duplication and Proliferation of Cerebellar Granule Neuron Progenitors

Granule neuron progenitors (GNPs) are the most abundant neuronal type in the cerebellum. GNP proliferation and thus cerebellar development require Sonic hedgehog (Shh) secreted from Purkinje cells. Shh signaling occurs in primary cilia originating from the mother centriole. Centrioles replicate only...

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Detalhes bibliográficos
Main Authors: Wu, Chuanqing, Yang, Mei, Li, Juan, Wang, Chengbing, Cao, Ting, Tao, Kaixiong, Wang, Baolin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176001/
https://ncbi.nlm.nih.gov/pubmed/25251415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107943
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