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Domain ChIRP reveals the modularity of long noncoding RNA architecture, chromatin interactions, and function

Little is known about the functional domain architecture of long RNA molecules, mainly because of a relative paucity of suitable methods to analyze RNA function at a domain level. Here we describe domain-specific chromatin isolation by RNA purification (dChIRP), a scalable technique to dissect pairw...

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Bibliographische Detailangaben
Hauptverfasser: Quinn, Jeffrey J, Ilik, Ibrahim A, Qu, Kun, Georgiev, Plamen, Chu, Ci, Akhtar, Asifa, Chang, Howard Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175979/
https://ncbi.nlm.nih.gov/pubmed/24997788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2943
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