The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China

BACKGROUND: The cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) gene is expressed in the vascular endothelium, which metabolizes arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs). 20-HETE mediates cardiovascular homeostasis and growth...

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Main Authors: Zou, Jin-Guo, Ma, Yi-Tong, Xie, Xiang, Yang, Yi-Ning, Pan, Shuo, Adi, Dilare, Liu, Fen, Chen, Bang-Dang
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175619/
https://ncbi.nlm.nih.gov/pubmed/25189712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-13-145
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