Design and in silico evaluation of an intraperitoneal–subcutaneous (IP–SC) artificial pancreas

Prandial glucose regulation is a major challenge for the artificial pancreas using subcutaneous insulin (without a feedforward bolus) due to insulin’s slow absorption-peak (50–60 min). Intraperitoneal insulin, with a fast absorption peak (20–25 min), has been suggested as an alternative to address t...

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Bibliographic Details
Main Authors: Lee, Justin J., Dassau, Eyal, Zisser, Howard, Doyle, Francis J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175509/
https://ncbi.nlm.nih.gov/pubmed/25267863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compchemeng.2014.02.024
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