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Oxygen and Glucose Deprivation in an Organotypic Hippocampal Slice Model of the Developing Rat Brain: The Effects on N-Methyl-d-Aspartate Subunit Composition

BACKGROUND: Oganotypic hippocampal slices (OHS) are commonly used to screen for neuroprotective effects of pharmacologic agents relevant to pediatric brain injury. The importance of donor rat pup age and N-methyl-d-aspartate (NMDA) receptor subunit composition have not been addressed. In this study...

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Detalhes bibliográficos
Main Authors: Wise-Faberowski, Lisa, Robinson, Prairie Neeley, Rich, Sarah, Warner, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175416/
https://ncbi.nlm.nih.gov/pubmed/19535712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e3181a27e37
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