Shutdown of Achaete-scute Homolog-1 Expression by Heterogeneous Nuclear Ribonucleoprotein (hnRNP)-A2/B1 in Hypoxia

The basic helix-loop-helix transcription factor hASH1, encoded by the ASCL1 gene, plays an important role in neurogenesis and tumor development. Recent findings indicate that local oxygen tension is a critical determinant for the progression of neuroblastomas. Here we investigated the molecular mech...

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Autors principals: Kasim, Mumtaz, Benko, Edgar, Winkelmann, Aline, Mrowka, Ralf, Staudacher, Jonas J., Persson, Pontus B., Scholz, Holger, Meier, Jochen C., Fähling, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175337/
https://ncbi.nlm.nih.gov/pubmed/25124043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579391
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