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Ciliary neurotrophic factor reduces proliferation and promotes differentiation of TH-MYCN transformed sympathoadrenal progenitors

Neuroblastoma is a childhood cancer caused by transformation of sympathoadrenal progenitors. By following the formation of tumors in homozygous TH-MYCN mice, an established mouse model of neuroblastoma, we were able to capture transformed cells prior to the formation of large, vascularized tumors in...

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Detalhes bibliográficos
Main Authors: DeWitt, John, Pappas, Anthony, Nishi, Rae
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175133/
https://ncbi.nlm.nih.gov/pubmed/25171250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365281
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