Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma
PURPOSE: To evaluate outer retinal structural abnormalities in patients with visual deficits following closed globe blunt ocular trauma (cgBOT). METHODS: Nine subjects with visual complaints following cgBOT were examined between 1 month post-trauma and 6 years post-trauma. Spectral domain optical co...
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2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175068/ https://ncbi.nlm.nih.gov/pubmed/24752010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IAE.0000000000000169 |
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pubmed-41750682015-10-01 Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma Flatter, John A. Cooper, Robert F. Dubow, Michael J. Pinhas, Alexander Singh, Ravi S. Kapur, Rashmi Shah, Nishit Walsh, Ryan D. Hong, Sang H. Weinberg, David V. Stepien, Kimberly E. Wirostko, William J. Robison, Scott Dubra, Alfredo Rosen, Richard B. Connor, Thomas B. Carroll, Joseph Retina Article PURPOSE: To evaluate outer retinal structural abnormalities in patients with visual deficits following closed globe blunt ocular trauma (cgBOT). METHODS: Nine subjects with visual complaints following cgBOT were examined between 1 month post-trauma and 6 years post-trauma. Spectral domain optical coherence tomography (SD-OCT) was used to assess outer retinal architecture, while adaptive optics scanning light ophthalmoscopy (AOSLO) was used to analyze photoreceptor mosaic integrity. RESULTS: Visual deficits ranged from central scotomas to decreased visual acuity. SD-OCT defects included focal foveal photoreceptor lesions, variable attenuation of the interdigitation zone, and mottling of the outer segment band, with one subject having normal outer retinal structure. AOSLO revealed disruption of the photoreceptor mosaic in all subjects, variably manifesting as foveal focal discontinuities, perifoveal hyporeflective cones, and paracentral regions of selective cone loss. CONCLUSIONS: We observe persistent outer retinal disruption in subjects with visual complaints following cgBOT, albeit to a variable degree. AOSLO imaging allows assessment of photoreceptor structure at a level of detail not resolvable using SD-OCT or other current clinical imaging tools. Multimodal imaging appears useful for revealing the cause of visual complaints in patients following cgBOT. Future studies are needed to better understand how photoreceptor structure changes longitudinally in response to various trauma. 2014-10 /pmc/articles/PMC4175068/ /pubmed/24752010 http://dx.doi.org/10.1097/IAE.0000000000000169 Text en |
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Article Flatter, John A. Cooper, Robert F. Dubow, Michael J. Pinhas, Alexander Singh, Ravi S. Kapur, Rashmi Shah, Nishit Walsh, Ryan D. Hong, Sang H. Weinberg, David V. Stepien, Kimberly E. Wirostko, William J. Robison, Scott Dubra, Alfredo Rosen, Richard B. Connor, Thomas B. Carroll, Joseph Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
description |
PURPOSE: To evaluate outer retinal structural abnormalities in patients with visual deficits following closed globe blunt ocular trauma (cgBOT). METHODS: Nine subjects with visual complaints following cgBOT were examined between 1 month post-trauma and 6 years post-trauma. Spectral domain optical coherence tomography (SD-OCT) was used to assess outer retinal architecture, while adaptive optics scanning light ophthalmoscopy (AOSLO) was used to analyze photoreceptor mosaic integrity. RESULTS: Visual deficits ranged from central scotomas to decreased visual acuity. SD-OCT defects included focal foveal photoreceptor lesions, variable attenuation of the interdigitation zone, and mottling of the outer segment band, with one subject having normal outer retinal structure. AOSLO revealed disruption of the photoreceptor mosaic in all subjects, variably manifesting as foveal focal discontinuities, perifoveal hyporeflective cones, and paracentral regions of selective cone loss. CONCLUSIONS: We observe persistent outer retinal disruption in subjects with visual complaints following cgBOT, albeit to a variable degree. AOSLO imaging allows assessment of photoreceptor structure at a level of detail not resolvable using SD-OCT or other current clinical imaging tools. Multimodal imaging appears useful for revealing the cause of visual complaints in patients following cgBOT. Future studies are needed to better understand how photoreceptor structure changes longitudinally in response to various trauma. |
author |
Flatter, John A. Cooper, Robert F. Dubow, Michael J. Pinhas, Alexander Singh, Ravi S. Kapur, Rashmi Shah, Nishit Walsh, Ryan D. Hong, Sang H. Weinberg, David V. Stepien, Kimberly E. Wirostko, William J. Robison, Scott Dubra, Alfredo Rosen, Richard B. Connor, Thomas B. Carroll, Joseph |
author_facet |
Flatter, John A. Cooper, Robert F. Dubow, Michael J. Pinhas, Alexander Singh, Ravi S. Kapur, Rashmi Shah, Nishit Walsh, Ryan D. Hong, Sang H. Weinberg, David V. Stepien, Kimberly E. Wirostko, William J. Robison, Scott Dubra, Alfredo Rosen, Richard B. Connor, Thomas B. Carroll, Joseph |
author_sort |
Flatter, John A. |
title |
Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
title_short |
Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
title_full |
Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
title_fullStr |
Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
title_full_unstemmed |
Outer Retinal Structure Following Closed Globe Blunt Ocular Trauma |
title_sort |
outer retinal structure following closed globe blunt ocular trauma |
publishDate |
2014 |
url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC4175068/ https://ncbi.nlm.nih.gov/pubmed/24752010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IAE.0000000000000169 |
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1800882686848401408 |