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Inhibition of endothelial lipase activity by sphingomyelin in the lipoproteins

Endothelial lipase (EL) is a major determinant of plasma HDL concentration, its activity being inversely proportional to HDL levels. Although it is known that it preferentially acts on HDL, compared to LDL and VLDL, the basis for this specificity is not known. Here we tested the hypothesis that sphi...

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Main Authors: Yang, Peng, Belikova, Natalia A., Billheimer, Jeff, Rader, Daniel J., Hill, John S., Subbaiah, Papasani V.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175046/
https://ncbi.nlm.nih.gov/pubmed/25167836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-014-3944-1
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