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Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells

OBJECTIVE: Patatin-like phospholipase domain containing 3 (PNPLA3, adiponutrin) has been identified as a modifier of lipid metabolism. To better understand the physiological role of PNPLA3/adiponutrin, we have investigated its regulation in intact mice and human hepatocytes under various nutritional...

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Detalhes bibliográficos
Principais autores: Hao, Lei, Ito, Kyoko, Huang, Kuan-Hsun, Sae-tan, Sudathip, Lambert, Joshua D., Ross, A. Catharine
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175036/
https://ncbi.nlm.nih.gov/pubmed/25060692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2014.06.016
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