Asymmetric Neuroblast Divisions Producing Apoptotic Cells Require the Cytohesin GRP-1 in Caenorhabditis elegans

Cytohesins are Arf guanine nucleotide exchange factors (GEFs) that regulate membrane trafficking and actin cytoskeletal dynamics. We report here that GRP-1, the sole Caenorhabditis elegans cytohesin, controls the asymmetric divisions of certain neuroblasts that divide to produce a larger neuronal pr...

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Bibliographic Details
Main Authors: Teuliere, Jerome, Cordes, Shaun, Singhvi, Aakanksha, Talavera, Karla, Garriga, Gian
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2014
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174935/
https://ncbi.nlm.nih.gov/pubmed/25053664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.167189
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