DNA Helicase HIM-6/BLM Both Promotes MutSγ-Dependent Crossovers and Antagonizes MutSγ-Independent Interhomolog Associations During Caenorhabditis elegans Meiosis

Meiotic recombination is initiated by the programmed induction of double-strand DNA breaks (DSBs), lesions that pose a potential threat to the genome. A subset of the DSBs induced during meiotic prophase become designated to be repaired by a pathway that specifically yields interhomolog crossovers (...

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Autori principali: Schvarzstein, Mara, Pattabiraman, Divya, Libuda, Diana E., Ramadugu, Ajit, Tam, Angela, Martinez-Perez, Enrique, Roelens, Baptiste, Zawadzki, Karl A., Yokoo, Rayka, Rosu, Simona, Severson, Aaron F., Meyer, Barbara J., Nabeshima, Kentaro, Villeneuve, Anne M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2014
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174932/
https://ncbi.nlm.nih.gov/pubmed/25053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.161513
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