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Validating Antibodies to the Cannabinoid CB2 Receptor: Antibody Sensitivity Is Not Evidence of Antibody Specificity

Antibody-based methods for the detection and quantification of membrane integral proteins, in particular, the G protein-coupled receptors (GPCRs), have been plagued with issues of primary antibody specificity. In this report, we investigate one of the most commonly utilized commercial antibodies for...

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Detalhes bibliográficos
Main Authors: Marchalant, Yannick, Brownjohn, Philip W., Bonnet, Amandine, Kleffmann, Torsten, Ashton, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174627/
https://ncbi.nlm.nih.gov/pubmed/24670796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155414530995
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