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Dephosphorylated-uncarboxylated Matrix Gla protein concentration is predictive of vitamin K status and is correlated with vascular calcification in a cohort of hemodialysis patients

BACKGROUND: Matrix Gla protein (MGP) is known to act as a potent local inhibitor of vascular calcifications. However, in order to be active, MGP must be phosphorylated and carboxylated, with this last process being dependent on vitamin K. The present study focused on the inactive form of MGP (dephos...

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Dettagli Bibliografici
Autori principali: Delanaye, Pierre, Krzesinski, Jean-Marie, Warling, Xavier, Moonen, Martial, Smelten, Nicole, Médart, Laurent, Pottel, Hans, Cavalier, Etienne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174604/
https://ncbi.nlm.nih.gov/pubmed/25190488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-145
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