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The Effects of Excipients on Protein Aggregation During Agitation: An Interfacial Shear Rheology Study

We investigated the effects of excipients in solutions of keratinocyte growth factor 2 (KGF-2) on protein aggregation during agitation as well as on interfacial shear rheology at the air-water interface. Samples were incubated with or without agitation, and in the presence or absence of the excipien...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Lu, Qi, Wei, Schwartz, Daniel K., Randolph, Theodore W., Carpenter, John F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174554/
https://ncbi.nlm.nih.gov/pubmed/23712900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23622
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