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Preferential Effect of Akt2-Dependent Signaling on the Cellular Viability of Ovarian Cancer Cells in Response to EGF

Objective: Overexpression of the epidermal growth factor receptor (EGFR) is associated with the malignant phenotype in many cancers including ovarian cancer, which leads to increased cell proliferation and survival. In spite of emerging EGFR inhibitors as a potentially useful agent, they are largely...

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Detalhes bibliográficos
Main Authors: Khabele, Dineo, Kabir, Syeda M, Dong, Yuanlin, Lee, Eunsook, Rice, Valerie Montgomery, Son, Deok-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174511/
https://ncbi.nlm.nih.gov/pubmed/25258648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.9688
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