MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes

OBJECTIVES: To assess the sensitivity of the phagocyte-specific molecules myeloid-related protein (MRP) 8 and MRP14 (calprotectin) for monitoring disease activity during anti-interleukin (IL)-1 therapies in patients with cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinf...

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Hoofdauteurs: Wittkowski, Helmut, Kuemmerle-Deschner, Jasmin B, Austermann, Judith, Holzinger, Dirk, Goldbach-Mansky, Raphaela, Gramlich, Katharina, Lohse, Peter, Jung, Thomas, Roth, Johannes, Benseler, Susanne M, Foell, Dirk
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174360/
https://ncbi.nlm.nih.gov/pubmed/21908452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2011.152496
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