Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts

OBJECTIVE: To analyse gene expression patterns and to define a specific gene expression signature in patients with the severe end of the spectrum of cryopyrin-associated periodic syndromes (CAPS). The molecular consequences of interleukin 1 inhibition were examined by comparing gene expression patte...

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Main Authors: Balow, James E, Ryan, John G, Chae, Jae Jin, Booty, Matthew G, Bulua, Ariel, Stone, Deborah, Sun, Hong-Wei, Greene, James, Barham, Beverly, Goldbach-Mansky, Raphaela, Kastner, Daniel L, Aksentijevich, Ivona
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174357/
https://ncbi.nlm.nih.gov/pubmed/23223423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-202082
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