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Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility

Many epithelial tissues expand rapidly during embryonic development while remaining surrounded by a basement membrane. Remodeling of the basement membrane is assumed to occur during branching morphogenesis to accommodate epithelial growth, but how such remodeling occurs is not yet clear. We report t...

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Bibliographic Details
Main Authors: Harunaga, Jill S., Doyle, Andrew D., Yamada, Kenneth M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174355/
https://ncbi.nlm.nih.gov/pubmed/25158168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.08.014
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