Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures

BACKGROUND: Anti-Hu and anti-Ri antibodies are paraneoplastic immunoglobulin (Ig)G autoantibodies which recognize cytoplasmic and nuclear antigens present in all neurons. Although both antibodies produce similar immunohistological labeling, they recognize different neuronal proteins. Both antibodies...

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Detalhes bibliográficos
Main Authors: Greenlee, John E, Clawson, Susan A, Hill, Kenneth E, Wood, Blair, Clardy, Stacey L, Tsunoda, Ikuo, Jaskowski, Troy D, Carlson, Noel G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174281/
https://ncbi.nlm.nih.gov/pubmed/25228406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0160-0
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