Overexpressed HIF-2α in Endothelial Cells Promotes Vascularization and Improves Random Pattern Skin Flap Survival

BACKGROUND: The local skin flap procedure is very useful for reconstruction. However, flap necrosis caused by circulatory failure can occur at its distal portion. Hypoxia-inducible factors (HIFs) in endothelial cells (ECs) help to maintain ECs and promote vascularization, and HIF-2α is abundantly ex...

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Detalhes bibliográficos
Main Authors: Morimoto, Atsushi, Tomita, Shuhei, Imanishi, Masaki, Shioi, Go, Kihira, Yoshitaka, Izawa-Ishizawa, Yuki, Takaku, Mitsuru, Hashimoto, Ichiro, Ikeda, Yasumasa, Nakanishi, Hideki, Tamaki, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2014
Assuntos:
Experimentals
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174206/
https://ncbi.nlm.nih.gov/pubmed/25289325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GOX.0000000000000083
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