Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose

BACKGROUND: Mebendazole (MBZ) is an extremely insoluble and therefore poorly absorbed drug and the variable clinical results may correlate with blood concentrations. The necessity of a prolonged high dose treatment of this drug increases the risk of adverse effects. METHODS: In the present study we...

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Detalhes bibliográficos
Main Authors: de la Torre-Iglesias, Paloma Marina, García-Rodriguez, Juan José, Torrado, Guillermo, Torrado, Susana, Torrado-Santiago, Santiago, Bolás-Fernández, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174045/
https://ncbi.nlm.nih.gov/pubmed/25258515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S65561
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