Inhibition of the central melanocortin system decreases brown adipose tissue activity

The melanocortin system is an important regulator of energy balance, and melanocortin 4 receptor (MC4R) deficiency is the most common monogenic cause of obesity. We investigated whether the relationship between melanocortin system activity and energy expenditure (EE) is mediated by brown adipose tis...

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Hauptverfasser: Kooijman, Sander, Boon, Mariëtte R., Parlevliet, Edwin T., Geerling, Janine J., van de Pol, Vera, Romijn, Johannes A., Havekes, Louis M., Meurs, Illiana, Rensen, Patrick C. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173995/
https://ncbi.nlm.nih.gov/pubmed/25016380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M045989
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