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Blood-Gene Expression Reveals Reduced Circadian Rhythmicity in Individuals Resistant to Sleep Deprivation

STUDY OBJECTIVES: To address whether changes in gene expression in blood cells with sleep loss are different in individuals resistant and sensitive to sleep deprivation. DESIGN: Blood draws every 4 h during a 3-day study: 24-h normal baseline, 38 h of continuous wakefulness and subsequent recovery s...

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Detalhes bibliográficos
Main Authors: Arnardottir, Erna S., Nikonova, Elena V., Shockley, Keith R., Podtelezhnikov, Alexei A., Anafi, Ron C., Tanis, Keith Q., Maislin, Greg, Stone, David J., Renger, John J., Winrow, Christopher J., Pack, Allan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173916/
https://ncbi.nlm.nih.gov/pubmed/25197809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.4064
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