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Abundant and Diverse Clustered Regularly Interspaced Short Palindromic Repeat Spacers in Clostridium difficile Strains and Prophages Target Multiple Phage Types within This Pathogen

Clostridium difficile is an important human-pathogenic bacterium causing antibiotic-associated nosocomial infections worldwide. Mobile genetic elements and bacteriophages have helped shape C. difficile genome evolution. In many bacteria, phage infection may be controlled by a form of bacterial immun...

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Autors principals: Hargreaves, Katherine R., Flores, Cesar O., Lawley, Trevor D., Clokie, Martha R. J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173771/
https://ncbi.nlm.nih.gov/pubmed/25161187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01045-13
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