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Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates
Heparan sulfates (HSs) are complex and highly active molecules that are required for synaptogenesis and long-term potentiation. A deficit in HSs leads to autistic phenotype in mice. Here, we investigated the long-term effect of heparinase I, which digests highly sulfated HSs, on the spontaneous bioe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4173299/ https://ncbi.nlm.nih.gov/pubmed/25225107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0134 |
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