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Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan

Perineuronal nets (PNs) in the brains of tenascin-R-deficient (tn-r(−/−)) mice develop in temporal concordance with those of wild-type (tn-r(+/+)) mice. However, the histological appearance of PNs is abnormal in adult tn-r(−/−) mice. Here, we investigated whether similar defects are also seen in dis...

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Detalhes bibliográficos
Main Authors: Morawski, Markus, Dityatev, Alexander, Hartlage-Rübsamen, Maike, Blosa, Maren, Holzer, Max, Flach, Katharina, Pavlica, Sanja, Dityateva, Galina, Grosche, Jens, Brückner, Gert, Schachner, Melitta
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173296/
https://ncbi.nlm.nih.gov/pubmed/25225104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0046
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