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Development of prediction tools for diarrhea and rash in breast cancer patients receiving lapatinib in combination with capecitabine

Lapatinib and capecitabine (L-CAP) is effective in HER-2 positive patients with metastatic breast cancer (MBC). However, moderate to severe diarrhea and rash (≥ grade 2) are problematic dose limiting toxicities. Since risk may vary over the course of therapy, we developed repeated measures models to...

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Detalhes bibliográficos
Main Authors: Dranitsaris, George, Lacouture, Mario E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173070/
https://ncbi.nlm.nih.gov/pubmed/25216762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3126-0
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