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Counter-flow elutriation of clinical peripheral blood mononuclear cell concentrates for the production of dendritic and T cell therapies

INTRODUCTION: Peripheral blood mononuclear cells (PBMC) concentrates collected by apheresis are frequently used as starting material for cellular therapies, but the cell of interest must often be isolated prior to initiating manufacturing. STUDY DESIGN AND METHODS: The results of enriching 59 clinic...

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Bibliographic Details
Main Authors: Stroncek, David F, Fellowes, Vicki, Pham, Chauha, Khuu, Hanh, Fowler, Daniel H, Wood, Lauren V, Sabatino, Marianna
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173057/
https://ncbi.nlm.nih.gov/pubmed/25223845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0241-y
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