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Reciprocal regulation of PCGEM1 and miR-145 promote proliferation of LNCaP prostate cancer cells

Prostate cancer gene expression marker 1 (PCGEM1) is a long non-coding RNA (lncRNA) overexpressed in prostate cancer (PCa) cells that promotes PCa initiation and progression, and protects against chemotherapy-induced apoptosis. The microRNA miR-145 functions as a tumor suppressor in PCa. We speculat...

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Détails bibliographiques
Auteurs principaux: He, Jin-Hua, Zhang, Jing-zhi, Han, Ze-Ping, Wang, Li, Lv, Yu Bing, Li, Yu-Guang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173053/
https://ncbi.nlm.nih.gov/pubmed/25200485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0072-y
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