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Tumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway

Aberrant expression of miR-1 has been implicated in various cancers. However, the mechanisms underlying the role of miR-1 in CRC progression still have not been clarified clearly. Here, we showed the decreased expression of miR-1 in colorectal carcinoma (CRC) tissues and cell lines. Ectopic introduc...

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Bibliografiske detaljer
Main Authors: Xu, Lijun, Zhang, Yue, Wang, Hui, Zhang, Guanhua, Ding, Yanqing, Zhao, Liang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172896/
https://ncbi.nlm.nih.gov/pubmed/25196260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0244-8
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