Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors

BACKGROUND: Platelet-derived growth factors (PDGFs) bind to two receptors, PDGFRα and PDGFRβ to mediate cell proliferation, migration and survival. Although epithelial cells typically do not express high levels of PDGFRs, their expression has been reported to increase in breast cancer cells that hav...

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Bibliografiske detaljer
Main Authors: Stalker, Leanne, Pemberton, James, Moorehead, Roger A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172847/
https://ncbi.nlm.nih.gov/pubmed/25253994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0089-5
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