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Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors
BACKGROUND: Platelet-derived growth factors (PDGFs) bind to two receptors, PDGFRα and PDGFRβ to mediate cell proliferation, migration and survival. Although epithelial cells typically do not express high levels of PDGFRs, their expression has been reported to increase in breast cancer cells that hav...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172847/ https://ncbi.nlm.nih.gov/pubmed/25253994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0089-5 |
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