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Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics
BACKGROUND: Autophagy is a vesicle-mediated pathway for lysosomal degradation, essential under basal and stressed conditions. Various cellular components, including specific proteins, protein aggregates, organelles and intracellular pathogens, are targets for autophagic degradation. Thereby, autopha...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172826/ https://ncbi.nlm.nih.gov/pubmed/25214434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0056-8 |
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