Exendin-4 ameliorates cardiac ischemia/reperfusion injury via caveolae and caveolins-3

BACKGROUND: Exendin-4, an exogenous glucagon-like peptide-1 receptor (GLP-1R) agonist, protects the heart from ischemia/reperfusion injury. However, the mechanisms for this protection are poorly understood. Caveolae, sarcolemmal invaginations, and caveolins, scaffolding proteins in caveolae, localiz...

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Hlavní autoři: Tsutsumi, Yasuo M, Tsutsumi, Rie, Hamaguchi, Eisuke, Sakai, Yoko, Kasai, Asuka, Ishikawa, Yoshihiro, Yokoyama, Utako, Tanaka, Katsuya
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172825/
https://ncbi.nlm.nih.gov/pubmed/25194961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-014-0132-9
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