N-Acetylcysteine Attenuates Hexavalent Chromium-Induced Hypersensitivity through Inhibition of Cell Death, ROS-Related Signaling and Cytokine Expression

Chromium hypersensitivity (chromium-induced allergic contact dermatitis) is an important issue in occupational skin disease. Hexavalent chromium (Cr (VI)) can activate the Akt, Nuclear factor κB (NF-κB), and Mitogen-activated protein kinase (MAPK) pathways and induce cell death, via the effects of r...

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Detalhes bibliográficos
Main Authors: Lee, Yu-Hsuan, Su, Shih-Bin, Huang, Chien-Cheng, Sheu, Hamm-Ming, Tsai, Jui-Chen, Lin, Chia-Ho, Wang, Ying-Jan, Wang, Bour-Jr
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172727/
https://ncbi.nlm.nih.gov/pubmed/25248126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108317
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