PAX6 Downregulates miR-124 Expression to Promote Cell Migration During Embryonic Stem Cell Differentiation

PAX6-null mice exhibit defects in multiple organs leading to neonatal lethality, but the mechanism by which this occurs has not yet fully elucidated. In this study, we generated induced pluripotent stem cells (iPSCs) from Pax6-mutant mice and investigated the effect of PAX6 on cell fate during embry...

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Dettagli Bibliografici
Autori principali: Fang, Jing, Zhang, Ting, Liu, Yinan, Li, Yang, Zhou, Shixin, Song, Daijun, Zhao, Yanxia, Feng, Ruopeng, Zhang, Xiaoyan, Li, Lingsong, Wen, Jinhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172463/
https://ncbi.nlm.nih.gov/pubmed/24773074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0410
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