PAX6 Downregulates miR-124 Expression to Promote Cell Migration During Embryonic Stem Cell Differentiation

PAX6-null mice exhibit defects in multiple organs leading to neonatal lethality, but the mechanism by which this occurs has not yet fully elucidated. In this study, we generated induced pluripotent stem cells (iPSCs) from Pax6-mutant mice and investigated the effect of PAX6 on cell fate during embry...

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Detalhes bibliográficos
Main Authors: Fang, Jing, Zhang, Ting, Liu, Yinan, Li, Yang, Zhou, Shixin, Song, Daijun, Zhao, Yanxia, Feng, Ruopeng, Zhang, Xiaoyan, Li, Lingsong, Wen, Jinhua
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172463/
https://ncbi.nlm.nih.gov/pubmed/24773074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0410
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