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Transforming Growth Factor β and Insulin Signal Changes in Stromal Fibroblasts of Individual Keratoconus Patients

Keratoconus (KC) is a complex thinning disease of the cornea that often requires transplantation. The underlying pathogenic molecular changes in this disease are poorly understood. Earlier studies reported oxidative stress, metabolic dysfunctions and accelerated death of stromal keratocytes in kerat...

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Detalhes bibliográficos
Main Authors: Foster, James, Wu, Wai-Hong, Scott, Sherri-Gae, Bassi, Mehak, Mohan, Divya, Daoud, Yassine, Stark, Walter J., Jun, Albert S., Chakravarti, Shukti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172437/
https://ncbi.nlm.nih.gov/pubmed/25247416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106556
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