Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections

Oropharyngeal candidiasis (OPC) is an opportunistic fungal infection caused by Candida albicans. OPC is frequent in HIV/AIDS, implicating adaptive immunity. Mice are naive to Candida, yet IL-17 is induced within 24 h of infection, and susceptibility is strongly dependent on IL-17R signaling. We soug...

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Autors principals: Conti, Heather R., Peterson, Alanna C., Brane, Lucas, Huppler, Anna R., Hernández-Santos, Nydiaris, Whibley, Natasha, Garg, Abhishek V., Simpson-Abelson, Michelle R., Gibson, Gregory A., Mamo, Anna J., Osborne, Lisa C., Bishu, Shrinivas, Ghilardi, Nico, Siebenlist, Ulrich, Watkins, Simon C., Artis, David, McGeachy, Mandy J., Gaffen, Sarah L.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172215/
https://ncbi.nlm.nih.gov/pubmed/25200028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130877
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