Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders

In the present study, we have investigated the functional profile of CD4 T cells from patients with common variable immunodeficiency (CVID), including production of cytokines and proliferation in response to bacteria and virus-derived antigens. We show that the functional impairment of CD4 T cells,...

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Autors principals: Perreau, Matthieu, Vigano, Selena, Bellanger, Florence, Pellaton, Céline, Buss, Guillaume, Comte, Denis, Roger, Thierry, Lacabaratz, Christine, Bart, Pierre-Alexandre, Levy, Yves, Pantaleo, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172212/
https://ncbi.nlm.nih.gov/pubmed/25225461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140039
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