Intranasal delivery of FSD-C10, a novel Rho kinase inhibitor, exhibits therapeutic potential in experimental autoimmune encephalomyelitis

Viewing multiple sclerosis (MS) as both neuroinflammation and neurodegeneration has major implications for therapy, with neuroprotection and neurorepair needed in addition to controlling neuroinflammation in the central nervous system (CNS). While Fasudil, an inhibitor of Rho kinase (ROCK), is known...

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Detalhes bibliográficos
Principais autores: Li, Yan-Hua, Yu, Jie-Zhong, Liu, Chun-Yun, Zhang, Hui, Zhang, Hai-Fei, Yang, Wan-Fang, Li, Jun-Lian, Feng, Qian-Jin, Feng, Ling, Zhang, Guang-Xian, Xiao, Bao-Guo, Ma, Cun-Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172138/
https://ncbi.nlm.nih.gov/pubmed/24749492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12303
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