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Soluble CD14 is essential for lipopolysaccharide-dependent activation of human intestinal mast cells from macroscopically normal as well as Crohn's disease tissue

Mast cells are now considered sentinels in immunity. Given their location underneath the gastrointestinal barrier, mast cells are entrusted with the task of tolerating commensal microorganisms and eliminating potential pathogens in the gut microbiota. The aim of our study was to analyse the responsi...

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Detalhes bibliográficos
Main Authors: Brenner, Sibylle A, Zacheja, Steffi, Schäffer, Michael, Feilhauer, Katharina, Bischoff, Stephan C, Lorentz, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172134/
https://ncbi.nlm.nih.gov/pubmed/24697307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12299
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