Synthesis of Pyrimidine Incorporated Piperazine Derivatives and their Antimicrobial Activity

Thiophene substituted chalcones (1a-e) were cyclised with thiourea in presence of potassium hydroxide to get 4-substituted-6-(thiophen-2-yl)pyrimidine-2-thiols (2a-e) which were then stirred with methyl iodide to obtain 4-substituted-2-(methylsulfanyl)-6-(thiophen-2-yl)pyrimidines (3a-e). Compounds...

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Bibliografske podrobnosti
Main Authors: Thriveni, K. S., Padmashali, B., Siddesh, M. B., Sandeep, C.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171870/
https://ncbi.nlm.nih.gov/pubmed/25284931
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